Miss Ludlow was an unapologetic hedonist, much like Mr. McCreedy. The loss of her soul was a gut punch. Nothing seemed to matter anymore. She used to be fascinated by the devils, wanted to know more about them and fell in love with the Quiet Deviless. I don’t know if it was hubris oder love, that led her believe that the Deviless wouldn’t take her soul… After a brief period of depression, nightmares and a gallon of honey, she eventually got it back. She is now a fierce supporter of the church. She became a soul shepard and does everything she can to undermine the work of the devils. So yes, the lack of a soul affected my roleplay deeply.
On another note, the loss itself was one of the most immersive situations that I experienced in Fallen London. Imho that says a lot about the game and the excellent writing.